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Human Immunodeficiency Virus (HIV): Signs And Symptoms - Health

Human immunodeficiency virus (HIV) can move through stages: acute HIV (stage 1), clinical latency (stage 2), and AIDS (stage 3). The symptoms of each stage can look different. Those in an early stage of HIV can have flu-like symptoms, while those in an advanced stage can have severe infections.   

HIV affects the immune system's ability to fight infections. You can get HIV or pass HIV to someone through blood, semen and pre-seminal fluid, rectal fluid, vaginal fluid, and breast milk that contains the virus. The virus is transmitted from person to person when these body fluids come into contact with your body's tissue, blood, or broken skin (e.G., open wounds).

The method of transmission of HIV can vary. You may get or pass HIV through:

  • Perinatal transmission from birth parent to child (i.E., through pregnancy, childbirth, or breastfeeding)
  • Sharing needles, syringes, and other drug injection equipment
  • Unprotected vaginal or anal sex
  • Acute (sudden) HIV starts two to four weeks after you get the virus. Acute HIV is also known as primary HIV. The virus multiplies very quickly in the immune system during this stage. Two-thirds of people in this stage experience flu-like symptoms, while some people don't have symptoms at all. Symptoms in the acute stage can last a few days to several weeks and may include: Chills Fatigue Fever Mouth ulcers Muscle aches Night sweats Rash Sore throat Swollen lymph nodes Symptoms can last a few days to several weeks. Acute-stage HIV symptoms can mimic other conditions, like the flu or common cold. It's important to not assume that you have HIV. You may consider getting tested for the virus if you think you may have been exposed to HIV. The clinical latency stage, or chronic HIV, is the second stage of HIV. The virus continues to multiply but much more slowly than in the acute stage during this stage. You might not experience any symptoms as a result. You can still transmit the virus to someone else even if you have no symptoms if you are not taking any treatment for HIV. People can stay in the clinical latency stage for an average of 10 years without treatment. Symptoms and disease progression vary from person to person. You can move through this stage more quickly or slowly than the average time. You can decrease your viral load (the amount of HIV that you have that you can transmit to someone else) to an undetectable level if you are taking treatments. This stage can last for several decades while you're on treatment. HIV can continue to slowly multiply and weaken your immune system over time and without treatment. This can result in the third and final stage of HIV: acquired immunodeficiency syndrome (AIDS), also known as late-stage HIV. AIDS symptoms include: Colored blotches or patches on or under the skin and inside the mouth, nose, and eyelids Depression Diarrhea that lasts for more than seven days Feeling extremely tired  Memory loss  Pneumonia Rapid weight loss (sometimes called wasting) Recurring fever Sores on the mouth, buttocks, and genitals Swollen lymph nodes in the armpits, neck, and groin that last a long time You may receive an AIDS stage diagnosis if: The number of CD4 cells in your blood falls below 200 cells per cubic millimeter of blood (200 cells/mm3). You develop one or more opportunistic infections regardless of how many CD4 cells you have. AIDS symptoms are often related to opportunistic infections (OIs) or an AIDS-defining illness. Certain illnesses occur more frequently and severely in people with AIDS. OIs occur when HIV has caused too much damage to the body's immune system and can no longer fight off infections. Some OIs include:  Taking HIV medications as prescribed can slow disease progression and prevent AIDS. You can live with AIDS for about three years without treatment. Your life expectancy can shorten to one year if you develop an OI and are not taking treatment.  Deciding whether to take treatment or not isn't always a choice. Not everyone has access to necessary healthcare services. This can be due to poverty, lack of insurance, racial disparities in the healthcare system, cultural stigma about HIV, and other factors. The only way to know if you have HIV is to get tested. Knowing your HIV status is a powerful way to help take care of yourself and your partners.  Keep in mind: Don't rely only on symptoms as a way to tell if you are living with HIV. HIV symptoms can mimic other conditions. You might not have any symptoms at all. Reach out to a healthcare provider or local clinic to learn more about testing if you think you may have been exposed to HIV. You can get a test for HIV at a healthcare provider's office, local health department, and family planning clinics, among others. You can also test for HIV at home. Testing is available for free if you have health insurance. Some testing sites still offer tests for free or on a sliding scale based on your income if you do not have insurance. Please visit HIV.Gov's testing overview here for more information about testing. Use the CDC resource here to find an HIV testing site near you.  HIV is a serious and chronic (long-lasting) condition that attacks and destroys CD4 cells in your immune system. HIV can progress through three stages: the acute stage, the clinical latency stage, and the AIDS stage. Your symptoms may change depending on your HIV's current stage.  It's good practice to get tested if you think you may have been exposed to HIV. Testing is the only way you can confirm a diagnosis and rule out other conditions. Thanks for your feedback!

    Dr Jessica Robinson-Papp Discusses Symptoms Indicating ... - AJMC

    Jessica Robinson-Papp, MD, MS, professor of neurology at Icahn School of Medicine at Mount Sinai, discusses how neurologic symptoms in individuals with HIV can present in various places in the body while also possibly pointing to a neurologic condition.

    Some neurologic symptoms in patients with HIV can be more obvious than others, says Jessica Robinson-Papp, MD, MS, professor of neurology at Icahn School of Medicine at Mount Sinai.

    Transcript

    What are some symptoms you look for in patients with HIV who you may suspect have a neurological complication of their HIV?

    That can be really broad, and some of the symptoms, I think, are more overt than others. So, for example, in patients who have advanced immunosuppression and AIDS and we're worried about an infection in the brain, some of the symptoms might be things like headache or confusion [or] seizures. If it's an infection, you could have fever and other kinds of systemic signs of infection.

    If it is a patient who is not particularly immunosuppressed, and has been doing well, often those neurologic complications are similar to somebody who didn't have HIV. In that case, you're just basically starting with the symptoms that the patient complains of. Some of the things that I see a lot of are peripheral neuropathies. Those patients will sometimes complain of pain or numbness or tingling in the bottoms of their feet or coming up their legs. That can be a common symptom.

    One of the other disorders that we see a lot of are HIV-associated neurocognitive disorders, which is abbreviated HAND, and those patients may report difficulty with different cognitive processes. So, maybe they're having trouble focusing like they used to, or handling their finances or their appointments or managing in their day-to-day life.

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    11 Common HIV Symptoms In Women - Signs Of HIV

    What if I told you that early HIV symptoms actually feel more like a common cold than anything else?

    "Most people who get infected don't even know. It's only in hindsight they recognize the symptoms," says Michael Horberg, M.D., director of HIV/AIDS for Kaiser Permanente.

    During the first few weeks after infection (a stage known as acute HIV infection or acute retroviral syndrome), some people notice things like fever, aches, and sore throat. But after acute infection, patients move into clinical latency stage, or chronic HIV, which is largely symptom-free.

    A refresher: HIV (a.K.A. Human immunodeficiency virus) is an incurable virus that attacks your body's immune system. It can be passed on through bodily fluids like semen, blood, and breast milk; though, not through saliva. When it comes HIV prevention, the CDC recommends using condoms or possibly exploring new medications like pre-exposure prophylaxis (PrEP) and post-exposure prophylaxis (PEP), which aim to prevent the transmission of HIV.

    While there is no cure for the disease, most HIV patients can still love long, healthy lives thanks to antiretroviral therapy (ART) treatments.

    An estimated 1.1 million people are living with HIV in the U.S.*

    However, left untreated, HIV can progress to AIDS (acquired immunodeficiency syndrome), which can make you even more susceptible to severe illnesses and eventually lead to death.

    The only way to really know whether you have HIV is to get tested (which you should be doing at least once a year if you're sexually active and have unprotected sex). There are two options for anonymous and confidential home testing, but you need to make sure your tests are FDA-approved and be aware that results are not always accurate (and may require a follow-up test if positive).

    Since early detection of HIV can prolong your lifespan and reduce your transmission rates, it's important to be aware of the potential symptoms (as well as the fact that, in most cases, there are no symptoms). Here's what you need to know about HIV symptoms in women:

    1. You have a fever and chills. A low-grade fever —99.5 to 101 F—accompanied by chills is one of the more common HIV symptoms you might notice. "Your body is trying to fight a foreign body that isn't supposed to be there, in this case ineffectively," says Horberg. While raising your body temperature does actually kill some weaker viruses, like the flu, it's not enough to wipe out HIV. The fever usually lasts for a week or two, but it can pop up for just a day. "If there's any chance you could have been infected, get tested," Horberg adds. 2. You're always waking up with night sweats.

    Getting damp on a muggy night without air conditioning is definitely not the same as night sweats, which result in puddles of sweat that'll make you want to change your sheets. "The body is trying to release off toxins," says Horberg.

    Although HIV can cause night sweats, plenty of other potential culprits do as well, including menopause, mononucleosis, and cancers like lymphoma and leukemia, says Horberg. So if you're soaking your sheets over the course of a few nights, definitely check in with your doctor.

    3. You're breaking out in a rash.

    Some people who experience HIV symptoms notice a light red rash all over their bodies, including their arms, torso, and legs—although it can appear in just one or two spots.

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    "It's a general redness, not discrete red bumps. If you've ever had a drug reaction rash, it's similar to that," says Horberg.

    It usually lasts at least a week, and most patients say it's not itchy; it's a reaction to fever along with your body's natural inflammation response as it fights off infection.

    4. Your throat is so sore.

    An inflammatory response to a serious viral infection can also cause your throat to become inflamed, making it hard to swallow. But unlike strep, your doctor won't spot patches of white, just redness and inflammation like you'd get with a cold.

    "Lots of viruses affect your throat," says Horberg; but if you're concerned about HIV, it's best to see a doctor about this one.

    5. You feel sleepy and achy all over. You might feel generally uncomfortable (and really fatigued) for at least a week after you're first infected with HIV, says Horberg. It's an unrelenting exhaustion—even going to work or just sticking to your daily routine will be a chore. "Everything hurts. It's hard to move, and you just can't make yourself comfortable," says Horberg. "Your body is fighting the HIV virus, and it's tired." 6. Your neck—and armpits, and groin—are swollen.

    Your lymph nodes—located in your neck, armpits, and groin—manufacture infection-fighting cells, and they're working overtime at the same time they're under direct attack from HIV. That's why over a third of people who've been exposed to the virus notice these glands appear bigger than normal, explains Horberg.

    If you feel several swollen lymph nodes in different locations, it's definitely a symptom to check with your doctor stat.

    7. You have a yeast infection.

    Yeast are microscopic fungi that naturally live in your mouth and vagina. When you're first infected with HIV, however, they can grow out of control, causing a yeast infection.

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    "Your body's own natural ability to fight other infections is being attacked," says Horberg.

    That said, conditions like diabetes also commonly cause yeast infections—and some women without any underlying diseases simply get yeast infections more often than others. So check in with your doc for treatment; if you think there's a chance you could have recently been infected with HIV, ask if you should get tested.

    8. You have a canker sore.

    Canker sores (a.K.A. Mouth ulcers) are tender, round, whitish pits in the lining of your mouth—and they can be caused by inflammation as your body tries to fight off HIV, says Horberg.

    They often cause a stinging sensation, and are more sensitive to acidic foods like lemons. It should be noted, however, that canker sores happen for a variety of different reasons too, like stress, food allergies, or hormonal changes.

    9. You start losing weight unexpectedly. In its later stages, untreated HIV causes what's known as wasting, or loss of fat and muscle mass, because the virus causes you to lose your appetite and prevents your body from absorbing nutrients, says Horberg. While the exact amount you'll shed varies, it's noticeable and often happens over a long period of time. "Often your friends and loved ones will comment that you're wasting away," says Horberg. "Typically, it doesn't happen in patients who have been treated well with modern medicines." 10. You actually get diagnosed with meningitis.

    As HIV disseminates through your central nervous system, it can cause viral meningitis, a swelling of the membranes that protect the brain and spinal cord, says Amesh Adalja, M.D., an infectious disease expert at Johns Hopskins Bloomberg School of Public Health. According to the CDC, common symptoms of viral meningitis include fever, irritability, lethargy, and vomiting.

    Cryptococcal meningitis is also commonly associated with HIV infections, though usually in later stages or in patients with AIDS. Most people are exposed to the cryptococcus fungus at some point, but a weakened immune system can't fight off exposure the way a healthy one can.

    11. Your stomach feels off.

    A trio of gastrointestinal symptoms—diarrhea, nausea, and vomiting—may also be a marker for initial HIV infection, says Amruta Padhye, M.D., an infectious disease specialist at the University of Missouri Health Care. "With rising viremia [levels of virus in the blood], the immune system is in a state of hyperactivation," she explains.

    Bottom line? Your GI distress might not be just a stomach bug, so get it checked out if you're at risk for HIV.

    *Source: Centers for Disease Control and Prevention.

    Headshot of Colleen de Bellefonds

    Colleen de Bellefonds is an American freelance journalist living in Paris, France, with her husband and dog, Mochi. She loves running, yoga, and wine, and is very particular about her baguettes. 






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