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What Does An HIV Rash Look Like And How Is It Treated?

An HIV rash is irritated skin that affects people who have HIV. It can be itchy, red or purple, or painful.

Most people who have HIV get a rash at some point. It's a common symptom that can happen in early (acute) or later stages of an HIV infection. Because your body's immune system is trying to fight off the first infection from HIV, the response can cause a rash. 

If you already have HIV, you may have a weakened immune system, which makes you and your skin more vulnerable to infections from bacteria, viruses, and parasites, which can cause an HIV rash.

If you take medications to treat HIV, some of those can also cause HIV rashes. 

photo of seborrheic dermatitis on man's face

Most HIV rashes aren't serious and will typically clear up in a few days to a few weeks, even without treatment.

If the rash is caused by your HIV medicine, you may need to try a new one. Talk to your doctor if the rash doesn't go away by itself.

When your body tries to fight off HIV, it can cause an HIV rash, but it's not the only symptom.

Other symptoms of an early HIV infection include:

These typically last about two weeks.

When to see a doctor

Because these symptoms can look and feel like other common conditions (such as the flu or an allergic reaction) and go away quickly, many people don't realize that they can be signs of an HIV infection. Once these early symptoms go away, you may not notice any others until much later.

If you have a rash and think you may have been exposed to HIV, don't wait. A blood test can easily tell whether you have the virus. The sooner you're diagnosed, the sooner you can begin treatment. Medications will help control the virus, keep your infection from becoming AIDS, and help you stay healthy and live longer. They'll also lower your risk of spreading HIV to other people.

Common HIV rashes (from left): Molluscum contagiosum, herpes zoster (shingles), and urticaria (hives).

Many things can cause an HIV rash. Here are some of the most common causes:

  • Acute HIV rash: When you're first exposed to HIV, your immune system responds to the infection, leading to rashes. 
  • Other infections: When your immune system is weakened from HIV, you're susceptible to skin infections from viruses, bacteria, and parasites.
  • Medications: Antiretroviral drugs for HIV can sometimes cause rashes.
  • Talk to your doctor about any HIV-related rashes, as some may be serious and need medical treatment.

    Rash is one of the most common symptoms in the early stages of the HIV infection, especially for people with light skin. 

    What it looks like:

  • Asymmetrical red or purple bumps
  • Flat or raised blotches or spots
  • Blisters
  • Places where it can show up on your body:

  • Chest
  • Face 
  • Hands 
  • Feet
  • Back
  • HIV weakens the cells that usually fight off infection. Over time, especially if you don't take your HIV medicines, your body may have a harder time fighting off infections that cause rashes.

    These can include:

    Syphilis. If this sexually transmitted infection isn't treated right away, you might get a rash, especially on the soles of your feet and the palms of your hands, two to eight weeks after infection.

    Molluscum contagiosum. This viral skin infection causes small, flesh-colored bumps that can appear anywhere on your body, though usually not on your hands or the soles of your feet. You could have an outbreak of 100 bumps or more. It's contagious, meaning you can pass it to someone by touching their skin, sharing towels or linens, or touching the same objects. Typically, the bumps go away on their own, but they may be larger and harder to treat for people with HIV or AIDS. Treatments for the HIV infection can help by boosting your immune system.

    Herpes viruses. These are common in people with HIV and AIDS, and it's harder for people who have weakened immune systems to stop flare-ups. Shingles (also known as herpes zoster) can cause a painful skin rash that looks like a stripe of water blisters. It can cover an entire side of your body, but your torso, arms, legs, and face are the most common areas. See your doctor quickly if you think you have shingles. The sooner you start the medications, the better they work. Pain relievers and antiviral medications can make you feel better and help clear it up faster. If you have shingles near your eyes and you don't get treatment, it can cause permanent damage. You can also get herpes simplex rashes around your mouth or genitals. Antiviral medications can help treat these.

    Kaposi's sarcoma. This is a type of skin cancer. It looks like dark spots that may be brown, purple, or red. It usually happens when someone has AIDS.

    Drugs that treat HIV and related infections can also trigger rashes. These often go away several days or weeks after you stop taking the drug. Talk with your doctor before stopping any medication.

    If you have a rash along with fever, fatigue, headache, muscle pains, upset stomach, vomiting, and belly pain, you might have a "hypersensitivity reaction," which can happen with several HIV medications, including:

  • Abacavir (Ziagen) and medications that have abacavir in them (Epzicom, Triumeq, and Trizivir)
  • Dolutegravir (Tivicay) and medications that have dolutegravir in them (Dovato, Juluca, and Triumeq)
  • Maraviroc (Selzentry)
  • Nevirapine (Viramune)
  • Raltegravir (Isentress)
  • Get medical help right away if you have those symptoms or if you have:

  • Fever
  • Painful red or purplish rash
  • Blisters that spread on your skin and around your mouth, nose, and eyes
  • These could be signs of Stevens-Johnson syndrome, a severe form of hypersensitivity reaction. It's rare but can be life-threatening.

    If you already know you have HIV and you develop a rash, call your doctor so they can find out whether your rash is caused by your HIV or something else.

    If you have symptoms of a rash and you've never been diagnosed with HIV but think you might have been exposed, contact a health care provider right away. They can offer an HIV test and possibly HIV postexposure prophylaxis (PEP) treatment that may help prevent HIV.

    Treating an HIV-related skin rash depends on the cause. If your rash appears when you're first diagnosed with HIV, you can try applying something like a hydrocortisone cream for itch relief. Antiretroviral therapy (ART) may also help you feel better and prevent new rashes by strengthening your immune system. 

    If your rash is caused by your HIV medication, including ART, talk to your doctor to see if stopping or switching medications could help clear it up. 

    Talk to your doctor about rashes caused by other infections or if you're not sure of the cause, as you may need steroids or other types of topical ointments to treat them. 

    Other things you can do to relieve symptoms of an HIV rash:

  • Talk with your doctor about over-the-counter medication, such as an antihistamine or hydrocortisone, to help with itching.
  • Don't take hot showers or baths.
  • Stay out of direct sunlight.
  • An HIV rash can show up as itchy, red bumps on your chest, back, face, or legs. The rash can be one of the first symptoms when you're infected with HIV. HIV rashes can also appear when you already have HIV, caused either by another infection or by some HIV medicines. Most HIV rashes aren't serious and may clear up on their own, but you should still tell your doctor if you have a rash because some do require medical treatment.

    Can an HIV rash last for months?

    The symptoms of an acute HIV rash can last for a few days to a few weeks, but it's unlikely to last for months. 

    At what stage does HIV cause skin problems?

    HIV can cause skin problems as soon as you're infected with the virus. Rashes are one of the earliest symptoms of an HIV infection.


    HIV Spreads Faster Despite Treatment Advances

    A comprehensive guide to understanding and managing HIV in 2025 hivPhoto credit: Shutterstock.Com / Krakenimages.Com Addressing America's rising HIV trends

    Recent statistics have unveiled troubling increases in HIV infection rates across the United States, particularly within diverse communities. This alarming trend highlights the importance of understanding HIV and staying informed about emerging tools for prevention and management.

    Understanding the HIV journey

    HIV progresses through distinct and challenging stagesHIV, or Human Immunodeficiency Virus, develops in stages, each requiring tailored approaches to care. The acute phase, occurring within weeks of exposure, often presents flu-like symptoms such as fever, fatigue, and sore throat. Unfortunately, these signs can be easily mistaken for other illnesses, leading many cases to go unnoticed.

    As the virus enters the chronic phase, symptoms may subside, but its quiet activity continues to weaken the immune system over several years. Without intervention, the infection can progress to Acquired Immunodeficiency Syndrome (AIDS), a severe condition marked by life-threatening infections and diseases due to a compromised immune system.

    Prevention strategies in modern healthcare

    New and traditional methods combine to combat HIV transmissionThe landscape of Human Immunodeficiency Virus prevention has been transformed by advancements in medicine. Pre-exposure Prophylaxis (PrEP), a daily medication for individuals at higher risk, has proven to be a game-changer. By blocking the virus's ability to establish infection, PrEP significantly reduces the likelihood of transmission.

    These innovations work best when paired with established prevention strategies. Safe sex practices, such as condom use, remain critical. Regular HIV testing also serves as a cornerstone of prevention, ensuring timely detection and intervention.

    Community outreach programs and education efforts play a vital role in making prevention tools accessible to marginalized populations disproportionately affected by Human Immunodeficiency Virus.

    Recognizing early warning signs

    Detecting HIV early is key to effective managementEarly detection of HIV offers the best opportunity to manage the condition and prevent its progression. Warning signs include:

  • Persistent fatigue that doesn't resolve with rest.
  • Unexplained fever lasting for several days.
  • Swollen lymph nodes, particularly in the neck or underarms.
  • Recurring night sweats and rapid weight loss.
  • However, the infection often develops without noticeable symptoms, especially in its early stages. This underscores the importance of routine screening for everyone, regardless of perceived risk or visible health concerns.

    Advanced testing options

    Evolving technologies bring testing to the forefrontTesting has become more accessible and user-friendly, with options tailored to individual needs. Traditional clinical testing remains a reliable choice, offering comprehensive results under the care of medical professionals.

    At-home testing kits have gained popularity as a convenient alternative, allowing individuals to maintain privacy while obtaining accurate results. These kits involve simple procedures, such as finger-prick blood samples or oral swabs, with results processed through certified laboratories.

    Regular testing not only benefits individuals but also helps reduce community-wide transmission rates by identifying and addressing cases early.

    Living with HIV

    Life with HIV is manageable thanks to medical advancementsModern Human Immunodeficiency Virus treatment focuses on antiretroviral therapy (ART), a highly effective regimen that controls the virus and prevents its progression. ART works by suppressing viral replication, enabling individuals to maintain healthy immune function. When followed consistently, ART can even reduce the viral load to undetectable levels, minimizing the risk of transmission.

    Regular medical monitoring is essential for tracking treatment effectiveness and addressing potential side effects. Beyond medication, holistic support plays a crucial role in HIV management. Access to mental health resources, peer support groups, and nutritional guidance helps individuals navigate life with HIV while maintaining physical and emotional well-being.

    The future of HIV care

    Continuous advancements offer hope for a brighter futureThe fight against Human Immunodeficiency Virus is far from over, but ongoing research and innovation provide promising prospects. Scientists are exploring next-generation treatments, including long-acting injectable medications that could replace daily pills. Advances in testing technology aim to make early detection even more accessible and accurate.

    Efforts to eliminate stigma and improve healthcare equity are also central to the future of HIV care. Public health campaigns work to increase awareness and reduce discrimination, creating environments where individuals feel safe seeking help and discussing their status.

    Empowering individuals and communities

    Knowledge and action are the best defenses against HIVTackling the challenges of rising Human Immunodeficiency Virus rates requires collective effort. By staying informed, using prevention tools, and prioritizing regular testing, individuals can protect themselves and others. Communities must continue to advocate for expanded access to education, healthcare, and support services, ensuring no one is left behind in the fight against Human Immunodeficiency Virus.

    The path forward involves blending innovation with compassion, empowering everyone to take control of their health and contribute to a world where HIV is no longer a threat.


    Signs And Symptoms Of STIs In Men

    In some cases, sexually transmitted infections (STIs) cause no noticeable symptoms. When they do occur, STI symptoms in males can include discharge, bleeding, painful blisters, and more.

    Knowing the signs and symptoms of STIs can be important. Early treatment can help prevent complications and prevent the infection from spreading to others.

    STIs often cause no noticeable symptoms, so it is possible to have one without knowing it. It may also be easy to mistake STI symptoms for those of another issue.

    A note about sex and gender

    Sex and gender exist on spectrums. This article will use the terms "male," "female," or both to refer to sex assigned at birth. Click here to learn more.

    Chlamydia is a bacterial STI that passes from person to person through anal, oral, or vaginal sex without a condom or other barrier method. In a male, chlamydia can develop in the urethra, rectum, or throat.

    Some call chlamydia a "silent" infection because people are often unaware that they have it. The majority of these infections in males cause no symptoms.

    If symptoms do occur in males, they arise several weeks after the infection develops.

    Common symptoms of chlamydia in the urethra include:

  • discharge from the penis
  • pain when urinating
  • burning or itching around the opening of the penis
  • pain and swelling in one or both testicles
  • Chlamydia in the rectum is less common and usually causes no symptoms, but it can cause:

  • rectal pain
  • bleeding
  • discharge
  • Oral chlamydia is generally asymptomatic, but may cause a sore throat.

    Treatment

    Treating chlamydia involves antibiotics. It may involve taking a single dose or a 7-day course of an antibiotic. Repeat infections are common so it is a good idea to have another test after completing the treatment.

    Men's health resources

    For more research-backed information and resources, visit our dedicated men's health hub.

    Herpes is an infection with the herpes simplex virus (HSV). There are two types of the virus, and they tend to affect different parts of the body:

  • HSV–1, also called oral herpes, causes cold sores in and around the mouth.
  • HSV–2 almost always passes on through sex without a condom or other barrier method and causes genital herpes. It may also past through skin-to-skin contact with areas that are infected.
  • Many people with herpes have no symptoms, and others may have difficulty identifying their symptoms. Mild herpes blisters can resemble insect bites, ingrown hairs, or razor burn.

    If they do arise, the symptoms typically appear 2 days to 3 weeks after exposure to the infection.

    Common symptoms of herpes in males include:

  • painful blisters or open sores in or around the mouth
  • blisters on the genitals, rectum, buttocks, or thighs
  • tingling, itching, or burning sensations around the blisters
  • body aches
  • a fever
  • a loss of appetite
  • swollen lymph nodes
  • Treatment

    There is no cure for herpes, and outbreaks of symptoms can reoccur over time. Treatments focus on managing the symptoms and extending the time between outbreaks.

    Gonorrhea is an infection with Neisseria gonorrhoeae bacteria. It often develops in the urethra, rectum, or throat, and the bacteria can transmit through vaginal, anal, or oral sex without a condom.

    Most males with gonorrhea have no symptoms. When gonorrhea in the urethra does cause symptoms, they usually appear within a week after the infection has developed.

    Symptoms of gonorrhea in the urethral area in males include:

  • painful urination
  • white, yellow, or gray discharge from the urethra
  • pain in the testicles, though this is less common
  • Symptoms of a rectal infection may include:

  • itching and soreness in the anus
  • painful bowel movements
  • bloody discharge from the anus
  • Treatment

    Healthcare professionals can treat gonorrhea with antibiotics. These can stop the infection from progressing, but they cannot reverse any damage already done.

    For this reason, anyone with symptoms of the infection or likely exposure to it should see a healthcare professional for testing right away.

    The medical community is becoming increasingly concerned about the rise of antibiotic-resistant gonorrhea. This resistance makes successful treatment much more difficult, if not impossible.

    Bacteria are also responsible for syphilis, which transmits through vaginal, anal, or oral sex without a condom or other barrier method. It can also transmit through contact with an infected area.

    Men who have sex with men (MSM) have a higher risk of contracting syphilis. According to WHO, 7.5% of MSM have syphilis compared to 0.5% of males in the general population.

    Many people with primary syphilis do not notice symptoms. When symptoms do occur, they usually appear 10 to 90 days after infection, with 21 days being the average.

    The symptoms of syphilis progress in stages known as primary, secondary, latent, and tertiary. Each stage has its own unique set of symptoms that can last for weeks, months, or even years.

    The symptoms of primary syphilis include:

  • a small, firm sore where the bacteria initially entered the body, usually on the penis, anus, mouth, or lips
  • sores can also appear on the fingers or buttocks
  • swollen lymph nodes in the neck, groin, or armpits
  • Secondary syphilis can cause the following signs and symptoms:

  • skin rashes on the palms of the hands or soles of the feet
  • large gray or white lesions in the mouth, anus, armpit, or groin
  • fatigue
  • headaches
  • a sore throat
  • swollen lymph nodes
  • hair loss
  • muscle aches
  • The latent, or "hidden," stage of syphilis, during which there are no visible symptoms, can last for several years.

    Tertiary syphilis is very rare. It can cause severe health complications that affect multiple organ systems. The symptoms of tertiary syphilis include:

  • meningitis
  • stroke
  • dementia
  • blindness
  • heart problems
  • numbness
  • psychiatric symptoms, such as confusion and personality changes
  • Treatment

    A healthcare professional may recommend an antibiotic called benzathine penicillin G to treat primary, secondary, and early latent syphilis. People who are allergic to penicillin will need to use a different antibiotic, such as doxycycline or ceftriaxone.

    Although antibiotics will prevent the infection from progressing, they cannot repair any permanent damage resulting from the infection.

    HPV generally does not cause any symptoms. However, it can cause serious health issues even without symptoms.

    According to the Centers for Disease Control and Prevention (CDC), 9 out of 10 cases of HPV clear on their own within 2 years without any adverse health issues. When it does not go away on its own, it can cause issues, such as warts or even certain types of cancer.

    The type of HPV that causes warts is not linked with cancer, however.

    Individuals should speak with a healthcare professional if they notice the following symptoms around their genitals, mouth, or throat:

  • unusual growths
  • warts
  • lumps
  • sores
  • HPV can spread without penetrative sex. It can also spread through skin-to-skin contact with infected areas and sharing sex toys.

    Treatment

    There is no specific treatment for the HPV virus. However, treatment is available for the health issues it can cause. For example, genital warts are treatable with prescription medications.

    HPV can also be preventable through getting vaccinated. The CDC recommends all children between the ages of 11 and 12 years old receive 2 doses of the HPV vaccine. If an individual is between the ages of 19 and 26, and has not received the vaccine, they can speak to their healthcare professional about getting it.

    HIV is a virus that attacks the body's immune cells. It spreads through some, but not all, bodily fluids, including semen, vaginal and anal fluids, and blood.

    The most common methods of transmission in the U.S. Are through anal or vaginal sex, or sharing needles, syringes, or other drug-related equipment.

    Many people with HIV experience flu-like symptoms within 2 to 4 weeks of developing the infection and may be mild or difficult to distinguish from conditions like the common cold. Common symptoms of HIV in males are:

  • a fever
  • a sore throat
  • a rash
  • headaches
  • Other symptoms may include:

  • fatigue
  • joint and muscle pain
  • swollen lymph nodes
  • nausea and vomiting
  • Treatment

    While there is no cure for HIV, treatments can prevent symptoms and transmission. They can also keep the infection from progressing to stage 3 HIV (AIDS).

    The treatments are called antiretroviral therapy, and they reduce the amount of the virus in the body. When the amount is so low that a test cannot detect it, this eliminates the risk of transmitting HIV.

    Hepatitis is inflammation of the liver, often due to a viral infection. One of the most common hepatitis viruses is the hepatitis B virus (HBV). It can pass on through blood, semen, and some other bodily fluids.

    Healthcare professionals classify each HBV infection as either acute, meaning that it is temporary and will last for a few weeks and resolve on its own, or chronic, in which case it is a severe, long term condition.

    Most people with hepatitis B have no symptoms. People with symptoms may easily mistake them for those of cold or flu, and they tend to appear about 90 days after the HBV infection develops.

    Hepatitis B signs and symptoms include:

  • a fever
  • fatigue
  • a loss of appetite
  • abdominal pain
  • nausea
  • vomiting
  • muscle and joint pain
  • jaundice, which causes dark urine and yellowing of the skin and the whites of the eyes
  • A vaccine can prevent hepatitis B, and the WHO recommends that all infants receive 2 to 3 doses of this vaccine.

    Treatment

    There is currently no treatment for acute hepatitis B. Medications can treat chronic hepatitis B, and research in this area is ongoing.

    People with chronic hepatitis B need regular checkups for signs of liver disease.

    STIs often cause no symptoms in males.

    Many STIs are treatable, and almost all are preventable.

    People can prevent STIs by using barrier protection, such as condoms or dental dams, during sex. Also, vaccines can prevent some strains of HPV and hepatitis B.

    Anyone who is sexually active and believes they may have ben exposed to an STI should seek medical attention.






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