Looking Back | NEJM - nejm.org

To the Editor: On reading the Clinical Problem-Solving article by Glick et al. (May 5 issue),1 I was surprised to see the following statement in reference to the use of colchicine in a patient with gout: "Colchicine...would be relatively contraindicated, because she has chronic kidney disease." According to The Renal Drug Handbook, fifth edition (2019),2 a publication used extensively by nephrologists and pharmacists to guide drug dosing in kidney disease, colchicine may be used at a dose of 500 μg three to four times per day up to a maximum of 3 mg per day, even in patients with a . . .

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