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skin hiv1 and hiv2 symptoms :: Article Creator Leukemia Rash Pictures And Symptoms The following images show some ways in which leukemia can affect the skin. More detail is below. Here are some of the skin rashes and symptoms a person may experience with leukemia. Petechiae and purpura Petechiae are tiny spots that occur when small blood vessels called capillaries break under the skin. They are less than 2 millimeters across. Larger areas are known as purpura. Petechiae and purpura can be early signs of leukemia, although they may happen for many other reasons. Leukemia disrupts the production of platelets, which usually enable blood to clot. As platelet levels fall, it becomes harder for them to block any burst capillaries. As a result, the blood can leak out into the skin. Petechiae and purpura may appear red, purple, or brown. On darker skin, they can be harder to spot, but they may be easier to see on lighter areas, such as the ...