Signs of STD

Houston (Precision Vaccinations) The U.S. Sexually Transmitted Infections (STI) National Strategic Plan includes, but is not limited to, vaccine and treatment research focused on chlamydia, gonorrhea, and Mpox. According to recent STI reports, additional clinical evaluations and research are needed for these diseases. For example, the U.S. Centers for Disease Control and Prevention (CDC) today announced a report describing New York City patients with Mpox who developed new lesions after completing oral treatment. This CDC report suggests that post-treatment lesions might occur more commonly than previously reported. During the 2022 Mpox outbreak in the U.S., TPOXX® (tecovirimat), an antiviral medication approved for the treatment of smallpox, was used as an investigational treatment for severe mpox. However, efficacy and optimal treatment duration are still being investigated in 2023. All ten patients received outpatient treatment from the...

When considering a new medication, it can be scary to read the list of potential risks and side effects. It can be especially concerning when a prescription drug that improves one condition ends up making another condition worse or introduces a new problem. You may be facing such a dilemma if you require treatment for high blood pressure (also known as hypertension) and are experiencing tinnitus ("ringing in the ears" and other sounds). Some—but not all—blood pressure medications are associated with tinnitus. "Tinnitus is the sensation of hearing a noise, such as buzzing or ringing, without that sound actually occurring in the environment," says Dr. Melissa E. Heche, AuD, a voice pathologist and musician specialist at New York Speech and Hearing. Tinnitus and hearing loss often coexist, but there are other potential causes of tinnitus, including medications, Heche explained. "These medications are referred to as 'ototoxic.' Many common m...

Published: April 28, 2023 Dear Colleague, Sonoma County Public Health (PH) requests your assistance in responding to alarming increases in congenital syphilis in California and Sonoma County. Over the last several years, California has experienced a steep increase in syphilis among females and in congenital syphilis (CS). Many local health jurisdictions (LHJs) are seeing high CS morbidity defined as a threshold of more than 8.4 CS cases per 100,000 live births. In Sonoma County, even 1 CS case per year puts us above the high morbidity threshold. In addition, significant racial disparities have been observed, as rates of early syphilis and congenital syphilis are significantly higher among Black/African American and American Indian/Alaska Native infants than the statewide rate. Congenital syphilis can be prevented with timely testing and treatment. A common risk factor, however, is receiving late or no prenatal care...

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No longer a death sentence, this STD can be treated successfully—but it must be diagnosed early. Syphilis is one of the oldest sexually transmitted diseases (STDs), with records revealing its existence dates back to medieval 15th-century Europe. Of course, back then we didn't have antibiotics, which meant a diagnosis of syphilis caused sufferers to look forward to a slow and miserable journey toward the grave. Nowadays, syphilis can be easily treated and cured long before it causes irreversible damage. Barbara Bawer, M.D., a family medicine physician at Ohio State University Wexner Medical Center, said there are four stages of syphilis Primary Secondary Latent Tertiary In general, syphilis almost never advances past the secondary stage in developed countries because its symptoms—rash, swollen lymph nodes, fever and so on—usually are obvious enough to encourage people to seek treatment. "The populations most affected have varied through the centuries, ...

MIT researchers have developed a wearable patch that applies painless ultrasonic waves to the skin, creating tiny channels that drugs can pass through. Credit: Courtesy of the researchers Using ultrasonic waves that propel drug molecules into the skin, the patch could be used to treat a variety of skin conditions. MIT MIT is an acronym for the Massachusetts Institute of Technology. It is a prestigious private research university in Cambridge, Massachusetts that was founded in 1861. It is organized into five Schools: architecture and planning; engineering; humanities, arts, and social sciences; management; and science. MIT's impact includes many scientific breakthroughs and technological advances. Their stated goal is to make a better world through education, research, and innovation. " data-gt-translate-attributes="[{"attribute":"data-cmtooltip", "format":"html"}]">MIT researchers ha...

New prescription rules around sodium valproate, announced in December 2022, have been called "out of proportion" by a coalition of epilepsy charities. The organisations, including Epilepsy Action, the International League Against Epilepsy (ILAE) and SUDEP Action, are calling for the Medicines and Healthcare products Regulatory Agency (MHRA) to pause its decision. Last year, the MHRA announced that no one under the age of 55 years should be prescribed sodium valproate unless two epilepsy specialists independently agree it's the only suitable medicine. The new rules include boys and men for the first time. In a public statement, the coalition said: "This is a dramatic shift in practice and risk for people with epilepsy without regard to each person's situation and life choices and totally out of proportion to the risks to patient safety." The group has also written to the Health Secretary Steve Barclay, sharing their concerns over the decision. No c...

Warning The Food and Drug Administration (FDA) warns that using kava has been associated with liver injury. Consult with your healthcare provider before using kava-containing supplements, especially if you have or have had liver problems, you frequently drink alcoholic beverages, or you take any prescription or over-the-counter (OTC) medications. Stop using kava if you develop symptoms that may indicate liver problems (e.g., yellowing of the skin or whites of the eyes, brown urine, light-colored stools, nausea, vomiting, unexplained tiredness, stomach pain, and loss of appetite). Kava, also known as Piper methysticum , is a shrub from the Piperacea (pepper) family. Traditionally, Pacific Islanders used kava extract as medicine and the beverage form of kava for religious and cultural ceremonies. Kava is promoted to relieve stress and anxiety due to its main active components (parts or ingredients) called kavalactones. The ways in which kavalactones work includes th...

Pharmaceuticals firm Granules India Ltd on Wednesday said it has received approval from the US health regulator for its generic gabapentin tablets indicated for management of postherpetic neuralgia in adults. The approval by the US Food & Drug Administration (USFDA) is for the abbreviated new drug application (ANDA) for Gabapentin tablets of strengths 600 mg and 800 mg, Granules India said in a regulatory filing. These tablets are bioequivalent to the reference listed drug product, Neurontin Tablets, 600 mg and 800 mg, of Viatris Specialty LLC. Gabapentin tablets are indicated for management of postherpetic neuralgia in adults; and as an adjunctive therapy in the treatment of partial onset seizures, with and without secondary generalisation, in adults and pediatric patients aged 3 years and older with epilepsy, the company added. Gabapentin tablets had annual sales of approximately USD 145 million in the US, it said citing IQVIA/IMS Health January 2023 data. Granules now has a ...

Wellbutrin (bupropion hydrochloride) is a brand-name drug that's prescribed for certain types of depression. This medication comes in sustained-release or extended-release oral tablets and is typically taken once or twice per day. The dosage can vary, depending on the condition the drug is used to treat. Wellbutrin belongs to a drug class called antidepressants. It's available in a generic version. This medication comes in two different forms: Wellbutrin sustained-release (SR) and Wellbutrin extended-release (XL) tablets. Both Wellbutrin SR and XL release medication slowly over time in your body. Wellbutrin isn't available as an immediate-release form. Keep reading for specific information about the dosage of Wellbutrin, including its strengths and how to take medication. For a comprehensive look at Wellbutrin, see this article. Note: This article describes typical dosages for Wellbutrin provided by the drug's manufacturer. When taking Wellbutrin, always follow the dosa...

April 12, 2023 – Cases of the sexually transmitted disease syphilis soared in 2021 to the highest total in more than 70 years, a new report says. Earlier this year, the CDC issued preliminary projections that syphilis rates had made a startling jump from 2020 to 2021. But now that health officials have finalized all of the 2021 data, the increase is worse than what was announced back in March. In just a 1-year period, from 2020 to 2021, cases increased by 32%, to 176,713, according to newly  finalized data from the CDC. That is the highest total number of syphilis cases the U.S. has seen since 1950. The total number of STD cases in the U.S. in 2021 was 2.5 million, including 1.6 million cases of chlamydia, which was up 4% over the year prior.  A CDC official labeled the situation an "epidemic." "The reasons for the ongoing increases are multifaceted – and so are the solutions," said Leandro Mena, MD, MPH, director of the C...

GRANITEVILLE, S.C. — Insight into East Palestine's future may be found nearly 600 miles away, in the small, southern town of Graniteville, S.C. What You Need To Know A Norfolk Southern train derailed in Graniteville, S.C. on Jan. 6, 2005 Seventeen cars derailed and one was punctured, releasing more than 9,000 gallons of liquid chlorine Nine people died and more than 5,000 were evacuated This is part one of a three-part series called Off the rails: Life after toxic train wrecks Spectrum News 1 Ohio also visited another derailment site in Paulsboro, N.J. to speak with residents as part of this same series "You know, I feel sorry for those people in Ohio," former Graniteville Fire Chief Phil Napier said. "Because they just don't know what they got ahead of them." According to the National Transportation Safety Board , on Jan. 6, 2005, Norfolk Southern freight train 192 derailed at 2:39 a.m. while traveling through Graniteville....

With all the recent advances in therapy for the chronic inflammatory and relapsing central facial dermatosis known as rosacea, the condition can nevertheless be very challenging to treat. Interestingly, many of the newer treatment approaches currently used in rosacea involve fine-tuning and tweaking the older medications that have already proven their therapeutic efficacy for the disease. The precise etiology of rosacea remains unclear, with neurovascular dysregulation, activation of the immune system, and infestation with Demodex mites being among the suggested pathophysiologic mechanisms. Subtype Presentation According to the clinical subtype and areas involved, rosacea is typically characterized by recurrent episodes of flushing (acute or subacute intermittent vasodilation) or transient erythema, persistent erythema, phymatous changes, papules, pustules, telangiectasias, as well as local edema and pain, burning, and ocular symptoms. Approximately 50% to 75% of patients with rosacea ...