Posts

Showing posts from February, 2023

Steglujan (Ertugliflozin and Sitagliptin) – Oral: Uses, Side Effects ... - Verywell Health

Image
What Is Steglujan? Steglujan ( ertugliflozin ; sitagliptin ) is an orally administered medication used in tandem with diet and exercise to improve blood glucose (blood sugar) levels in adults with type 2 diabetes. Steglujan contains two medications from two different classes of drugs: ertugliflozin, a sodium-glucose cotransporter 2 (SGLT2) inhibitor, and sitagliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor. Steglujan's active ingredients work together to help improve blood sugar control. SGLT2 inhibitors lower blood sugar levels by causing more sugar to leave the body in the urine. Comparatively, DPP-4 inhibitors decrease blood sugar levels by stimulating insulin release. Insulin is a hormone that helps sugar move from the blood to inside the cells. DPP-4 inhibitors cause the liver to produce less sugar. No generic product containing the two active ingredients in Steglijan, ertugliflozin and sitagliptin, is available. Steglujan is a bran...

Symptoms, diagnosis and treatment of gonorrhea - Emergency Live International

Image
Worldwide, it is the second most common bacterial sexually transmitted infection (STI) after chlamydia. Gonorrhea can be transmitted to both men (the gonococcus localizes in the urethra) and women (the bacterium is found in the vaginal fluid of the cervix) through any type of unprotected sexual intercourse (vaginal, anal and oral). Gonorrhea can be transmitted if infected sex toys are shared that are not properly sterilized or not covered with a new condom In women, the main symptoms involve burning and difficulty urinating, greenish-yellow discharge, pain during or after intercourse, vaginal itching and/or difficulty urinating. In men, it is manifested by the appearance of urethritis involving profuse and thick greenish-yellow discharge, burning sensation, and difficulty urinating. It is a condition that can be treated with antibiotic treatments, which can be accompanied by supplements and the application of natural substances that accelerate healing. Symptoms of gonorrhea...

Trends in HIV incidence following scale-up of harm reduction ... - The Lancet

Image
Total 3685 8976.2 473 5.3 4.8–5.8 n/a PWUD 692 1295.2 13 1.0 0.6–1.7 1 non-PWUD 716 1414.4 16 1.1 0.7–1.8 1.24 0.62–2.48 0.548 PWID 2277 6266.5 444 7.1 6.5–7.8 7.68 4.59–12.85 <0.001 Male 2896 7288.42 447 6.1 5.6–6.7 1 Female 789 1687.7 26 1.5 1.0–2.3 0.25 0.17–0.38 <0.001 Among PWID only  Male PWID 2246 6173.4 436 7.1 6.4–7.8 1  Female PWID 31 93.1 8 8.6 4.3–17.2 1.21 0.60–2.43 0.601  Age <25 yrs 777 1587.1 152 9.6 8.2–11.2 1  Age ≥25 yrs 1500 4679.5 292 6.2 5.6–7.0 0.69 0.60–0.83 <0.001  Hopin 773 2144.8 139 6.5 5.5–7.7 1  Mogaung 962 3076.8 186 6.0 5.2–7.0 0.95 0.76–1.18 0.646  Myitkyina 542 1044.9 119 11.4 9.5–13.6 1.73 1.35–2.21 <0.001  2008–2011 365 139.6 27 19.3 13.3–28.2 1  2012–2016 975 1253.7 165 13.2 11.3–15.3 0.66 0.44–1.00 0.053  2017–2020 937 4873.3 252 5.2 4.6–5.9 0.28 0.18–0.42 <0.001  Length of follow-up <3 yrs 2277 2468.4 262 10.6 9.4–12.0 1  Length of follow-up ≥3 yrs a Baseline was client enrolment, and length of foll...

Evenity vs. Prolia: What's the difference? - Medical News Today

Image
Evenity (romosozumab-aqqg ) and Prolia (denosumab) are brand-name prescription medications. They're approved by the Food and Drug Administration (FDA) to treat osteoporosis in certain people. Specifically, both drugs are used to treat osteoporosis in females who have gone through menopause and have a high risk of broken bones. This article reviews the key similarities and biggest differences between Evenity and Prolia. If you're considering treatment with one of these medications, talk with your doctor. By reviewing the risks and benefits, you can help decide whether either medication is right for you. For more comprehensive information about these two drugs, you can refer to our Evenity and Prolia articles. Note : Sex and gender exist on spectrums. Use of the terms "female" and "male" throughout this article refers to sex assigned at birth. Key differences between Evenity and Prolia These are a few of the main differences between Evenity and Prolia: Dosage:...

Why Have Congenital Syphilis Cases Risen 900% in Mississippi? - Healthline

Image
Share on Pinterest bojanstory/Getty Images Cases of congenital syphilis have tripled in recent years. The disease occurs when a mother who has syphilis passes the bacteria to their baby during pregnancy. Congenital syphilis is caused by a bacteria, called Treponema pallium, that can be transmitted from a pregnant person to their baby, even if the parent has received treatment. Cases of congenital syphilis have increased significantly over the past few years. In 2020, 2,000 cases were reported — the highest number of cases reported in a year since 1994. Mississippi recently reported a 900% increase in cases, according to hospital billing data shared with NBC News. Many other states, including California, Minnesota, and New Mexico, have reported alarming increases as well. The disease occurs when a mother who is infected with syphilis passes the bacteria to their baby during pregnancy. And though many mothers and babies many be asymptomatic, some will develop serious health issues, lik...

Enbrel (Etanercept) Subcutaneous: Uses, Side Effects, Dosages - Verywell Health

Image
What Is Enbrel? Enbrel ( etanercept ) is a tumor necrosis factor (TNF) receptor blocker used to treat several autoimmune conditions, such as rheumatoid arthritis, psoriatic arthritis, plaque psoriasis, and others. In autoimmune diseases, the immune system attacks itself and causes symptoms such as pain and swelling. As a TNF inhibitor, Enbrel affects the immune system by binding to TNF alpha and TNF beta, rendering TNF inactive. TNF is a substance in the body that causes inflammation. Enbrel is available as a subcutaneous (under the skin) injection. Drug Facts Generic Name :   Etanercept Brand Name(s) : Enbrel, Erelzi, Eticovo Drug Availability: Prescription Administration Route :   Subcutaneous Therapeutic Classification :   Immunosuppressants Available Generically :   No Controlled Substance :   N/A Active Ingredient :   Etanercept Dosage Form(s) : Solution What ...