Long-Term Aspirin Use Before Diagnosis May Reduce Risk of Death From Colorectal Cancer - Cancer Therapy Advisor
Long-term regular aspirin use before a diagnosis of colorectal cancer (CRC) is associated with a lower risk of CRC-specific mortality, according to a study published in the Journal of the National Cancer Institute. The study authors noted that long-term aspirin use has been shown to reduce the incidence of CRC, but there is no evidence on aspirin use and mortality outcomes in CRC patients. With that in mind, the researchers prospectively analyzed patients from the Cancer Prevention Study-II Nutrition Cohort who were cancer-free at baseline in 1992 or 1993 and were diagnosed with CRC during follow-up through 2015. Continue Reading The researchers looked at pre- and postdiagnosis use of aspirin. The prediagnosis cohort included 2686 participants, and the postdiagnosis cohort included 1931 participants. Patients reported information on aspirin use via questionnaires given at baseline, in 1997, and every 2 years thereafter. Regular aspir...